HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news

Cheap flights from Knoxville (TYS) to Missouri from $73

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — STL
Jun 17 — Jun 241
From?
To?
Mon 6/17
Mon 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

How far in advance should I book a flight from Knoxville to Missouri?

To save on the cost of your flight from Knoxville to Missouri, book at least 44 days before your planned departure. Booking around this time can save you about 36% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $267 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $464.

What is the cheapest month to fly from Knoxville to Missouri?

Our data shows that April tends to be the cheapest month to fly to Missouri from Knoxville. Users have commonly found prices around $341 for the month, but tickets can be as low as $214. Due to multiple factors, prepare for potentially higher prices in June.

What is the cheapest time of day to fly from TYS to MO?

When flying from Knoxville to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Cheap Knoxville to Missouri flights in June & July 2024

Find cheap flight options from Knoxville to Missouri specifically for the months of June and July 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 3,117,830 searches. Prices were last updated on June 12, 2024.
Check out some of the best flight deals from Knoxville to Missouri in 2024. More deals are always being added, so be sure to check back regularly.
Thu 7/186:30 amTYS - STL
1 stop11h 59mMultiple Airlines
Tue 7/2310:11 amSTL - TYS
1 stop9h 25mMultiple Airlines
Deal found 6/10$179
Wed 7/312:09 pmTYS - STL
1 stop5h 11mDelta
Wed 7/102:16 pmSTL - TYS
1 stop6h 09mDelta
Deal found 6/11$198
Tue 7/94:44 pmTYS - SGF
1 stop4h 44mAmerican Airlines
Tue 7/166:08 pmSGF - TYS
1 stop4h 54mAmerican Airlines
Deal found 6/10$208
Wed 7/107:48 pmTYS - STL
1 stop25h 09mFrontier
Mon 7/157:33 pmSTL - TYS
1 stop11h 29mFrontier
Deal found 6/11$212
Sun 7/285:25 amTYS - STL
1 stop4h 37mDelta
Sat 8/35:34 pmSTL - TYS
1 stop3h 40mDelta
Deal found 6/11$213
Tue 7/910:27 pmTYS - STL
1 stop11h 16mFrontier
Thu 7/118:57 pmSTL - TYS
1 stop23h 39mFrontier
Deal found 6/11$214
Thu 7/186:30 amTYS - STL
1 stop11h 59mMultiple Airlines
Tue 7/2310:11 amSTL - TYS
2 stops25h 44mMultiple Airlines
Deal found 6/10$220
Tue 7/211:21 amTYS - MCI
1 stop6h 11mAmerican Airlines
Sat 7/66:00 amMCI - TYS
1 stop8h 32mAmerican Airlines
Deal found 6/12$223
Thu 7/115:10 amTYS - STL
1 stop4h 20mAmerican Airlines
Mon 7/155:46 pmSTL - TYS
1 stop5h 16mAmerican Airlines
Deal found 6/11$237

Knoxville to Missouri 2024 flight deals

Discover exclusive flight deals for travel between Knoxville and Missouri in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 3,117,830 searches. Data last updated June 12, 2024.
Check out some of the best flight deals from Knoxville to Missouri in 2024. More deals are always being added, so be sure to check back regularly.
Thu 8/14:52 pmTYS - STL
1 stop16h 44mFrontier
Wed 8/77:33 pmSTL - TYS
1 stop13h 14mFrontier
Deal found 6/12$158
Fri 8/910:36 pmTYS - MCI
1 stop10h 05mFrontier
Sat 8/108:41 amMCI - TYS
1 stop11h 22mFrontier
Deal found 6/12$168
Thu 7/186:30 amTYS - STL
1 stop11h 59mMultiple Airlines
Tue 7/2310:11 amSTL - TYS
1 stop9h 25mMultiple Airlines
Deal found 6/10$179
Wed 7/312:09 pmTYS - STL
1 stop5h 11mDelta
Wed 7/102:16 pmSTL - TYS
1 stop6h 09mDelta
Deal found 6/11$198
Wed 9/42:15 pmTYS - SGF
1 stop5h 49mAmerican Airlines
Sat 9/76:27 pmSGF - TYS
1 stop4h 23mAmerican Airlines
Deal found 6/11$198
Tue 7/94:44 pmTYS - SGF
1 stop4h 44mAmerican Airlines
Tue 7/166:08 pmSGF - TYS
1 stop4h 54mAmerican Airlines
Deal found 6/10$208
Wed 7/107:48 pmTYS - STL
1 stop25h 09mFrontier
Mon 7/157:33 pmSTL - TYS
1 stop11h 29mFrontier
Deal found 6/11$212
Sun 7/285:25 amTYS - STL
1 stop4h 37mDelta
Sat 8/35:34 pmSTL - TYS
1 stop3h 40mDelta
Deal found 6/11$213
Tue 7/910:27 pmTYS - STL
1 stop11h 16mFrontier
Thu 7/118:57 pmSTL - TYS
1 stop23h 39mFrontier
Deal found 6/11$214

Knoxville to Missouri flights leaving soon

Find last-minute flight options from Knoxville to Missouri for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 3,117,830 searches. Data last updated June 12, 2024.
Consider one of these great deals we found on last-minute flights from Knoxville to Missouri. Users should examine the flight details to ensure there are no surprises.
Tue 6/185:25 amTYS - STL
1 stop4h 45mDelta
Sat 6/225:25 pmSTL - TYS
1 stop5h 28mDelta
Deal found 6/12$255
Thu 6/207:19 pmTYS - MCI
1 stop14h 36mMultiple Airlines
Tue 6/255:10 amMCI - TYS
1 stop11h 12mMultiple Airlines
Deal found 6/11$280
Thu 6/207:19 pmTYS - MCI
1 stop14h 36mMultiple Airlines
Tue 6/256:05 pmMCI - TYS
2 stops17h 50mMultiple Airlines
Deal found 6/11$289
Sat 6/227:30 amTYS - STL
1 stop10h 58mMultiple Airlines
Sun 6/236:55 pmSTL - TYS
2 stops25h 19mMultiple Airlines
Deal found 6/11$294
Mon 6/1710:41 pmTYS - MCI
1 stop10h 34mFrontier
Sat 6/228:41 amMCI - TYS
1 stop7h 18mFrontier
Deal found 6/12$308
Mon 6/1710:41 pmTYS - MCI
1 stop10h 34mFrontier
Fri 6/217:44 pmMCI - TYS
1 stop20h 15mFrontier
Deal found 6/12$328
Thu 6/203:20 pmTYS - MCI
2 stops15h 49mMultiple Airlines
Tue 6/256:05 pmMCI - TYS
2 stops17h 50mMultiple Airlines
Deal found 6/11$332
Thu 6/203:20 pmTYS - MCI
2 stops15h 49mMultiple Airlines
Mon 6/245:10 amMCI - TYS
1 stop9h 15mMultiple Airlines
Deal found 6/11$359
Thu 6/206:30 amTYS - MCI
3 stops27h 25mMultiple Airlines
Tue 6/256:05 pmMCI - TYS
2 stops17h 50mMultiple Airlines
Deal found 6/11$385

One-way flights to Missouri from Knoxville

Search for one-way flight options from Knoxville to Missouri. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 3,117,830 searches. Data last updated June 12, 2024.
Users in need of a one-way flight from Knoxville to Missouri can choose from these deals. Users can also find round-trip Knoxville to Missouri flights by using the search form above.
Wed 6/197:47 pmTYS - STL
1 stop19h 45mFrontier
Deal found 6/12$73
Sat 9/212:15 pmTYS - STL
1 stop5h 15mAmerican Airlines
Deal found 6/12$99
Tue 7/27:40 pmTYS - MCI
1 stop4h 17mAmerican Airlines
Deal found 6/12$99
Wed 6/197:47 pmTYS - STL
1 stop19h 45mFrontier
Deal found 6/11$103
Tue 6/1810:26 pmTYS - STL
1 stop9h 59mFrontier
Deal found 6/12$104
Sun 7/284:52 pmTYS - STL
1 stop16h 51mFrontier
Deal found 6/12$123
Sat 9/212:52 pmTYS - STL
2 stops6h 48mAmerican Airlines
Deal found 6/12$134
Tue 7/25:50 amTYS - MCI
2 stops9h 45mUnited Airlines
Deal found 6/12$139
Thu 6/206:21 amTYS - STL
1 stop6h 55mAmerican Airlines
Deal found 6/11$166

Find flights from Knoxville to Missouri within your budget

Customize your flight search to find flights from Knoxville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 3,117,830 searches. Data last updated June 12, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$158 - $280

Route

Depart

Return

Price

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 8/1

1 stop16h 44m

Lambert-St Louis

Wed 8/7

1 stop13h 14m

$158

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 7/18

1 stop11h 59m

Lambert-St Louis

Tue 7/23

1 stop9h 25m

$179

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Wed 7/3

1 stop5h 11m

Lambert-St Louis

Wed 7/10

1 stop6h 09m

$198

Knoxville McGhee TysonSpringfield-Branson

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Wed 9/4

1 stop5h 49m

Springfield-Branson

Sat 9/7

1 stop4h 23m

$198

Knoxville McGhee TysonSpringfield-Branson

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Tue 7/9

1 stop4h 44m

Springfield-Branson

Tue 7/16

1 stop4h 54m

$208

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Wed 7/10

1 stop25h 09m

Lambert-St Louis

Mon 7/15

1 stop11h 29m

$212

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Sun 7/28

1 stop4h 37m

Lambert-St Louis

Sat 8/3

1 stop3h 40m

$213

Knoxville McGhee TysonLambert-St Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 7/18

1 stop11h 59m

Lambert-St Louis

Tue 7/23

2 stops25h 44m

$220

Knoxville McGhee TysonSpringfield-Branson

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Mon 9/23

1 stop4h 44m

Springfield-Branson

Thu 9/26

1 stop6h 46m

$280

Flights are sorted by cheapest first

Deals found on 6/12

No data available for this route at this time. Please check back soon.

Best time to book a flight from Knoxville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 12, 2024.
Get a feel of what it's like to fly with Frontier, American Airlines and Delta from Knoxville to Missouri by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
10,000 reviews

Food

7.4

Comfort

7.9

Crew

8.6

Boarding

8.2

Entertainment

8.0

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Delta
8.0
Very good
10,000 reviews
Delta
8.0
Very good
10,000 reviews

Food

7.4

Comfort

7.9

Crew

8.6

Boarding

8.2

Entertainment

8.0

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Allegiant Air
7.5
Good
989 reviews
Delta
8.0
Very good
10,000 reviews

Food

7.4

Comfort

7.9

Crew

8.6

Boarding

8.2

Entertainment

8.0

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

United Airlines
7.4
Good
10,000 reviews
Delta
8.0
Very good
10,000 reviews

Food

7.4

Comfort

7.9

Crew

8.6

Boarding

8.2

Entertainment

8.0

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

American Airlines
7.3
Good
10,000 reviews
Delta
8.0
Very good
10,000 reviews

Food

7.4

Comfort

7.9

Crew

8.6

Boarding

8.2

Entertainment

8.0

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Frontier
6.2
Okay
3,957 reviews
Delta
8.0
Very good
10,000 reviews

Food

7.4

Comfort

7.9

Crew

8.6

Boarding

8.2

Entertainment

8.0

Overall

8.0

Reviews

1 / 10

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Missouri?

    For a flight from Knoxville to Missouri, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • Can I find flights from Knoxville to Missouri for under $200 on Cheapflights?

    Yes, there are multiple flights from Knoxville to Missouri for under $200. The cheapest flight booked recently is on Frontier for just $158, but on average you can expect to pay $217.

  • Are there last-minute flights available from Knoxville to Missouri for under $300?

    There are currently 20+ open flights from Knoxville to Missouri within the next 7 days for less than $300.

  • What are the cheapest airlines to fly from Knoxville to Missouri one-way?

    $73 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $99 and $139, respectively.

  • What are the most popular routes from Knoxville to Missouri?

    While some choose either Knoxville McGhee Tyson - Lambert-St Louis or Knoxville McGhee Tyson - Springfield-Branson, Knoxville McGhee Tyson - Kansas City is the most popular route from Knoxville to Missouri.

  • What does TYS to STL mean?

    Great question - TYS to STL just means Knoxville McGhee Tyson Airport to Lambert-St Louis Airport. Now you’ll know what these unique codes when you look for flights! Kansas City Airport (MCI), Springfield-Branson Airport (SGF), Columbia Regional Airport (COU), Kansas City Downtown Airport (MKC), Branson Airport (BKG) are some additional IATA codes for airports related to your trip.

  • Can I find deals for flights from Knoxville to Missouri that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to Missouri flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to Missouri with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to Missouri flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to Missouri that include hotel bookings?

    Yes. In addition to deals on Knoxville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Missouri.

  • Can I find deals for business class flights from Knoxville to Missouri?

    Yes. Cheapflights offers flight deals from Knoxville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to Missouri that allow pets onboard?

    Many airlines flying from Knoxville to Missouri offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to Missouri?

    Yes, you can often find last-minute deals on Knoxville to Missouri flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to Missouri flight deals updated?

    The Knoxville to Missouri flight deals you see on this page were last updated on 6/12.

  • What is the cheapest month to book a flight from Knoxville to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Missouri (average of $318). Flying from Knoxville to Missouri in July is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Missouri
See prices for flight routes from nearby airports that may be better suited for you.

Nashville to Seattle flights
Nashville to Newark flights
Nashville to Las Vegas flights
Nashville to LaGuardia flights
Nashville to John F Kennedy Intl flights
Nashville to O'Hare Intl flights
Nashville to Los Angeles flights
Nashville to Orlando flights
Memphis to LaGuardia flights
Nashville to Denver flights
Nashville to Fort Lauderdale flights
Memphis to Las Vegas flights
Memphis to Los Angeles flights
Knoxville to Omaha flights
Memphis to Newark flights
Nashville to Omaha flights
Memphis to O'Hare Intl flights
Knoxville to O'Hare Intl flights
Nashville to Dallas/Fort Worth flights
Memphis to John F Kennedy Intl flights
Memphis to Orlando flights
Memphis to Miami flights
Nashville to Boston flights
Nashville to Miami flights
Knoxville to Denver flights
Nashville to Hobby flights
Memphis to Denver flights
Nashville to Dulles Intl flights
Knoxville to LaGuardia flights
Nashville to Baltimore flights
Nashville to Ontario flights
Nashville to Salt Lake City flights
Nashville to Tampa flights
Nashville to Burbank flights
Nashville to Midway flights
Memphis to Boston flights
Nashville to Philadelphia flights
Nashville to Honolulu flights
Nashville to Reagan-National flights
Memphis to Seattle flights
Memphis to Hobby flights
Nashville to George Bush Intcntl flights
Nashville to Detroit flights
Knoxville to John F Kennedy Intl flights
Memphis to Dallas/Fort Worth flights
Memphis to Fort Lauderdale flights
Nashville to Minneapolis flights
Nashville to San Francisco flights
Memphis to Reagan-National flights
Nashville to Atlanta flights

Top 2 airlines flying from Knoxville to Missouri

Discover the top 2 airlines that operate flights from Knoxville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 3,117,830 searches. Data last updated June 12, 2024.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$206Average$375FlexibilityNo cancel feeOn-time71%
DeltaCheapest$229Average$426FlexibilityNo cancel feeOn-timeN/A
New York to Amsterdam flights
Denver to Atlanta flights
Los Angeles to New York flights
USA to Manila flights
Los Angeles to Orlando flights
Denver to Fort Lauderdale flights
Newark Airport to London flights
USA to Philippines flights
USA to Kathmandu flights
Honolulu to Maui flights
Atlanta to Houston flights
Knoxville to Mississippi flights

Search flights from Knoxville to Missouri by cabin class

Find flights from Knoxville to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
First Class
Business Class
Prem Econ Class
Economy Class

Book a flight to one of these trending destinations

User searches for flights to these destinations increased 20% or more in the past 90 days compared to other destinations
Flights to Naxos
Flights to Urumqi
Flights to Kaunas
Flights to Hyannis Barnstable
Flights to Brainerd Crow Wing County
Flights to Figari-Sud Corse
Flights to Komatsu
Flights to Riverton
Flights to Hakodate
Flights to Trabzon
Flights to Surigao
Flights to Pellston Emmet County
Flights to Constanţa Mihail Kogalniceanu
Flights to Neiva La Marguita
Flights to Liberal
Flights to Virac
Flights to Devils Lake
Flights to Edremit/Korfez
Flights to Alghero-Fertilia
Flights to Gaziantep
Flights to Paleochori Milos
Flights to Rhinelander Oneida County
Flights to Nampula
Flights to Leh
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
View all available airlines